Article Summary

Title : Multi-channel shot noise and characterization of cortical network activity
Authors : Michelle Rudolph and Alain Destexhe
Year : 2005
Journal : Neurocomputing
Volume : 65
Pages : 641-646


Neurons in cerebral cortex are characterized by a stochastic subthreshold membrane potential (Vm) activity, which originates from the ongoing and irregular activity of neurons in the cortical network. Here, we propose a way of characterizing this network activity by using the notion of shot noise applied to pulse-based kinetic models of synaptic conductances. We linkthe statistical characterization of synaptic conductances in terms of their mean and variance to the activity in the network, in particular the average ?ring rate of presynaptic neurons and their temporal correlation, thus providing a possible method for characterizing cortical networkactivity from intracellularly recorded Vm activity.