Yves Frégnac

Brief Bibliography :

   Yves Frégnac is Research Director (Exceptional Class) at the Centre National de la Recherche Scientifique (CNRS). He is currently Head of the CNRS interdisciplinary department that he has founded in 1999 (Unité de Neuroscience, Information et Complexité (UNIC)) and co-director of the Federative Institute Alfred Fessard of Neurobiology (INAF), located on the Life Science CNRS Campus in Gif sur Yvette. He is also Full Professor in the Department of Humanities and Social Sciences at the Ecole Polytechnique, near Paris and teaches at the interface between Neuroscience, Physics and Computer Science. His interdisciplinary research explores the phenomenon of complexity related to the natural dynamics of biological computation in visual cortical neural networks. Yves Frégnac has been the Biology coordinator for three European integrated projects, in the framework of the Future Emerging Technology (FET) Program of the European Community. Several teams of his department are now involved in the Human Brain Flagship Project, for which he acts as the CNRS coordinator. Yves Frégnac was awarded the Grand Prix thématique de l'Académie des Sciences (Prix Jaffé) in 1999 and the Grand Prix de l'Institut de France (Prix Louis D.) in 2008.

 

Ongoing Research :

   Information coding in sensory neurons is both digital, in terms of neuronal output spike timing, and analog, produced by the slower, subthreshold changes in somatic and dendritic membrane potential resulting from a continual barrage of synaptic inputs. These small and ever-changing voltage fluctuations in the neuronal membrane potential of the single neuron, control its excitability and spiking reliability. Intracellular recordings give access to the multiscale complexity in sensory processing. Reverse engineering analysis of these synaptic echoes allows indeed to retrieve at the same time the mesoscopic functional effective connectivity of the contextual network within which each cell is embedded, and the local microscopic processing realized by the single neuron.

   By varying and controlling the visual statistics simulated by a virtual oculomotor exploration of our visual environment, we were able to show that the time precision of the code, the reliability of the evoked dynamics of the visual cortical network and the functional organization of visual cortical receptive fields all adapt to the statistics of the sensory signals. Our observations are best explained by an homeostatic representation principle, where complexities of the input statistics and of V1 receptive field organization covary inversely. Generalized recruitment by the stimulus of center-surround interactions and local non-linearities tend to reduce the contextual noise in subthreshold dynamics of the single cortical neuron through a divisive shunt effect. Dynamic full field interactions are shown to regularize the functionally expressed organization of V1 receptive fields, making them more linear and “Simple”-like.

   Combination of intracellular recordings and network imaging (voltage sensitive dye) further allowed to explore binding mechanisms operating beyond the classical receptive field, in the “silent” periphery of visual cortical neurons. Using apparent motion noise at saccadic speed, we have inferred from the synaptic echoes (recorded intracellularly) the existence of long-distance propagation of visually evoked activity through lateral (and possibly feedback) connectivity outside the classical receptive field. VSD imaging has been used to visualize, at the mesoscopic level, the propagation patterns travelling at the speed inferred from our microscopic recordings. Our results demonstrate the propagation at the V1 map level of intracortical depolarizing waves, broadcasting an elementary form of collective “belief” to distant parts of the network. The functional features of these slow waves support the hypothesis of a dynamic perceptual association field, facilitating synaptic modulation in space and time during oculomotor exploration. They may serve as a substrate for implementing the psychological Gestalt principles of common fate and axial collinearity.

   We conclude from this review that the early visual system is far from being understood, and that the functional dynamics of visual cortical networks show a much higher level of complexity than initially thought. Comparison between different levels of integration not only shows how limited is our understanding of the emergence of feature selective maps in primary visual areas, but reveals unexpected immergence processes through which collective order regulates more microscopic properties in a top down fashion.

Work supported by CNRS, the French National Research Agency (NatStats and V1-complex) and the European Community (FE-Bio-I3 integrated programs (IP FP6: FACETS (015879), IP FP7: BRAINSCALES(269921) and Brain-i-nets (243914)); The Human Brain Project).

 

Selection of References :

Frégnac, Y. and Imbert, M. (1984). Development of neuronal selectivity in primary visual cortex of cat. Physiological Reviews 64 : 325-434

Frégnac, Y., Shulz, D., Thorpe, S. and Bienenstock, E. (1988). A cellular analog of visual cortical plasticity. Nature. 333 : 367-370.

Borg-Graham, L.J., Monier, C. and Frégnac, Y. (1998). Visual input evokes transient and strong shunting inhibition in visual cortical neurons. Nature. 393 : 369-373.

Bringuier, V ., Chavane, F., Glaeser, L. and Frégnac, Y. (1999). Horizontal propagation of visual activity in the synaptic integration field of area 17 neurons. Science. 283 : 695-699.

Monier, C., Chavane, F., Baudot, P., Graham, L.J. and Frégnac, Y. (2003). Orientation and Direction selectivity of synaptic activity in visual cortical neurons : a diversity of combinations produces spike tuning. Neuron. 37 : 663-680.

Romain Brette, Zuzanna Piwkowska, Cyril Monier, Michelle Rudolph, Julien Fournier, Manuel Levy, Yves Frégnac, Thierry Bal and Alain Destexhe (2008) High-Resolution Intracellular Recordings Using a Real-Time Computational Model of the Electrode, Neuron 59: 379-391.

Cyril Monier, Julien Fournier and Yves Frégnac (2008). In vitro and in vivo measures of evoked excitatory and inhibitory conductance dynamics in sensory cortices, Journal of Neuroscience Methods 169: 323-365.

Giorgio A. Ascoli, Lidia Alonso-Nanclares, Stewart A. Anderson, German Barrionuevo , Ruth Benavides-Piccione, Andreas Burkhalter, György Buzsáki, Bruno Cauli, Javier DeFelipe, Alfonso Fairén, Dirk Feldmeyer, Gord Fishell, Yves Frégnac, Tamas F. Freund, Daniel Gardner, Esther P. Gardner, Jesse H. Goldberg, Moritz Helmstaedter, Shaul Hestrin, Fuyuki Karube, Zoltán F. Kisvárday, Bertrand Lambolez, David A. Lewis, Oscar Marin, Henry Markram, Alberto Muñoz, Adam Packer, Carl C. H. Petersen, Kathleen S. Rockland, Jean Rossier, Bernardo Rudy, Peter Somogyi, Jochen F. Staiger, Gabor Tamas, Alex M. Thomson, Maria Toledo-Rodriguez, Yun Wang, David C. West and Rafael Yuste (2008). Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex, Nature Reviews Neuroscience 9: 557-568.

Marre, O., Yger, P., Davison, A.P. and Frégnac, Y. (2009). Reliable recall of spontaneous activity patterns in chaotic cortical networks. The Journal of Neuroscience, 2009, 29(46): 14596-14606.

El Boustani S. , Marre O. , Béhuret S. , Baudot P. , Yger P. , Bal T. , Destexhe A. and Frégnac Y. (2009) Network-state modulation of power-law frequency-scaling in visual cortical neurons, PLoS Computational Biology 5: e10005519 (with cover).

Frégnac, Y. Pananceau, M., René, A., Huguet, N., Marre, O., Levy M. and D.E. Shulz (2010). A re-examination of Hebbian-covariance rules and spike timing-dependent plasticity in cat visual cortex in vivo. Frontiers in Synaptic Neuroscience. 2: 147 1-21.

Chavane, F., Sharon, D., Jancke, D., Marre, O., Frégnac, Y. and Grinvald, A. (2011). Lateral spread of orientation selectivity in V1 is controlled by intracortical cooperativity. Frontiers in System Neuroscience, 5:4. 1-26.

Fournier, J., Monier, C., Pananceau, M. and Frégnac, Y. (2011). Adaptation of the Simple or Complex nature of V1 receptive fields to visual statistics. Nature Neuroscience. 14: 1053-1060.

Frégnac, Y. (2012). Reading out the synaptic echoes of low level perception in V1. Lecture Notes in Computer Science. 7583: 486-495.

Sami El Boustani, Pierre Yger, Alain Destexhe and Yves Frégnac (2012) Stable learning in stochastic network states, The Journal of Neuroscience 32: 194-214.

Manuel Levy, Julien Fournier and Yves Frégnac (2013).The role of delayed suppression in slow and fast contrast adaptation in v1 simple cells, The Journal of Neuroscience 33(15): 6388-400.

Béhuret S., Deleuze C., Gomez L., Frégnac Y., and Bal T. (2013). Cortically-controlled population stochastic facilitation as a plausible substrate for guiding sensory transfer across the thalamic gateway. PLoS Computational Biology 9(12): 1-27.

Arduin, P-J, Frégnac, Y., Shulz, DE and Ego-Stengel, V (2013). "Master" neurons induced by operant conditioning in rat motor cortex during a brain-machine interface task. The Journal of Neuroscience. 33(19): 8308-20.

Baudot, P, Levy, M., Marre, O., Monier C., Pananceau, M. and Y. Frégnac. (2014). Natural scenes evoke high temporal precision and low noise in V1. Frontiers in Neural Circuits 7: 206: 1-29.

Fournier, J., Monier, C., Levy, M., Marre, O., Sári, K., Kisvárday Z.F. and Frégnac, Y. (2014) Hidden Complexity of Synaptic Receptive Fields in Cat Primary Visual Cortex. The Journal of Neuroscience. 34 (16): 5515-5528. (with cover).


Links :

 

 

UNIC : http://www.unic.cnrs-gif.fr

 

FACETS and FACETS-ITN : http://facets.kip.uni-heidelberg.de/ITN/

 

Brain-i-nets: http://brain-i-nets.kip.uni-heidelberg.de

 

BrainScales : http://brainscales.kip.uni-heidelberg.de/

 

 

 

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Articles (84)

2016

Florian Gerard-Mercier, Pedro Carelli, Marc Pananceau, Xoana Troncoso and Yves Frégnac, Synaptic Correlates of Low-Level Perception in V1, Journal of Neuroscience 36: 3925–3942, (2016) [pdf] [PubMed]

Hugot Raguet, Cyril Monier, Luc Foubert, Isabelle Ferezou, Yves Frégnac and Gabriel Peyré, Spatially Structured Sparse Morphological Component Separation for Voltage-Sensitive Dye Optical Imaging, Journal of Neuroscience Methods 257: 76-96, (2016)

2015

Yves Frégnac and Brice Bathellier, Cortical Correlates of Low-Level Perception: From Neural Circuits to Percepts, Neuron 88(1): 110-126, (2015) [PubMed]

2014

Pierre-Jean Arduin, Yves Frégnac, Daniel Shulz and Valerie Ego-Stengel, Bidirectional control of a one-dimensional robotic actuator by operant conditioning of a single unit in rat motor cortex, Frontiers Neurosciences : 25;8:206. doi: 10.3389/, (2014)

Julien Fournier, Cyril Monier, Manuel Levy, Olivier Marre, Zoltán F. Kisvárday and Yves Frégnac, Hidden complexity of synaptic receptive fields in cat V1, J Neurosciences 16;34(16): 5515-28, (2014)

2013

Sébastien Béhuret, Charlotte Deleuze, Leonel Gomez-Sena, Yves Frégnac and Thierry Bal, Cortically-Controlled Population Stochastic Facilitation as a Plausible Substrate for Guiding Sensory Transfer across the Thalamic Gateway, PLOS Computational biology, 2013, PLOS computational biology 9: e1003401, (2013) [abstract]

Manuel Levy, Julien Fournier and Yves Frégnac, The role of delayed suppression in slow and fast contrast adaptation in v1 simple cells, J Neurosci 33(15): 6388-400, (2013) [pdf]

Pierre-Jean Arduin, Valerie Ego-Stengel, Yves Frégnac and Daniel Shulz, Master neurons induced by operant conditioning in rat motor cortex during a brain-machine interface task, J. Neurosci. 33(19): 8308-20, (2013) [pdf]

2012

Yves Frégnac, Reading out the synaptic echoes of low level perception in V1, Lecture Notes in Computer Science 7583: 486-495, (2012)

Sami El Boustani, Pierre Yger, Alain Destexhe and Yves Frégnac, Stable learning in stochastic network states, The Journal of Neuroscience 32: 194-214, (2012) [pdf]

2011

Frédéric Chavane, D Sharon , D Jancke, Olivier Marre, Yves Frégnac and A Grinvald, Lateral Spread of Orientation Selectivity in V1 is Controlled by Intracortical Cooperativity, Front Syst Neurosci 5: 4 1-26, (2011) [pdf]

Nicolas Schmidt, Gabriel Peyré and Yves Frégnac, Dissipative Wave Model Fitting Using Localized Sources, Waves : , (2011) [pdf]

Julien Fournier, Cyril Monier, Marc Pananceau and Yves Frégnac, Adaptation of the simple or complex nature of V1 receptive fields to visual statistics, Nature Neuroscience 14: 1053-1060, (2011) [pdf] [abstract] [PubMed]

Pierre Yger, Sami El Boustani, Alain Destexhe and Yves Frégnac, Topologically invariant macroscopic statistics in balanced networks of conductance-based integrate-and-fire neurons., Journal of Computational Neuroscience 31: 229-245, (2011) [pdf] [abstract]

2010

Nicolas Schmidt, Gabriel Peyré and Yves Frégnac, Separation of traveling waves in cortical networks using optical imaging., IEEE international conference on Biomedical imaging: from nano to Macro, ISBI’10 : 868-871, (2010)

Edvard I. Moser, Maurizio Corbetta, Robert Desimone, Yves Frégnac, Pascal Fries, A M. Graybiel, John-Dylan Haynes, Laurent Itti, Lucia Melloni, Hannah Monyer, Wolf Singer, Christoph Von Der Malsburg and Matthew Wilson, Coordination in the brain, Dynamic Coordination in the Brain: From Neurons to Mind , Strüngmann Forum Report 5: 193-214, (2010)

Yves Frégnac, Pedro Carelli, Marc Pananceau and Cyril Monier, Stimulus-driven Coordination of Cortical Cell Assemblies and Propagation of Gestalt Belief in V1, Dynamic Coordination in the Brain: From Neurons to ind, Strüngmann Forum Report 5: 169-192, (2010)

Yves Frégnac, Marc Pananceau, Alice René, Nazied Huguet, Olivier Marre, Manuel Levy and Daniel Shulz, A re-examination of Hebbian-covariance rules and spike timing-dependent plasticity in cat visual cortex in vivo, Front. Syn. Neurosci. 2: 147 1-21, (2010) [pdf]

2009

Olivier Marre, Pierre Yger, Andrew Davison and Yves Frégnac, Reliable recall of spontaneous activity patterns in chaotic cortical networks., The Journal of Neuroscience 29(46): 14596-14606, (2009)

Yves Frégnac, Multiscale functional imaging: reconstructing network dynamics from the synaptic echoes recorded in a single visual cortex neuron, Bull Acad Natl Med. 193(4): 851-862, (2009)

Olivier Marre, Sami El Boustani, Yves Frégnac and Alain Destexhe, Prediction of Spatiotemporal Patterns of Neural Activity from Pairwise Correlations, PHYSICAL REVIEW LETTERS 102: 138101-1 - 138101-4, (2009) [pdf] [abstract]

Sami El Boustani, Olivier Marre, Sébastien Béhuret, Pierre Baudot, Pierre Yger, Thierry Bal, Alain Destexhe and Yves Frégnac, Network-state modulation of power-law frequency-scaling in visual cortical neurons, PLoS Computational Biology 5:: e10005519, (2009) [pdf] [abstract]

Estelle Lucas-Meunier, Cyril Monier, Muriel Amar, Gérard Baux, Yves Frégnac and Philippe Fossier, Involvement of Nicotinic and Muscarinic Receptors in the Endogenous Cholinergic Modulation of the Balance between Excitation and Inhibition in the Young Rat Visual Cortex, Cerebral Cortex 19 : 2411-2427, (2009) [pdf] [abstract]

2008

Martin Pospischil, Cyril Monier, Yves Frégnac, Henry Markram and Alain Destexhe, Hodgkin-Huxley type models for different classes of cortical and thalamic neurons. , Biological Cybernetics 99: 427-441, (2008)

Giorgio A. Ascoli, Lidia Alonso-Nanclares, Stewart A. Anderson, German Barrionuevo , Ruth Benavides-Piccione, Andreas Burkhalter, György Buzsáki, Bruno Cauli, Javier DeFelipe, Alfonso Fairén, Dirk Feldmeyer, Gord Fishell, Yves Frégnac, Tamas F. Freund, Daniel Gardner, Esther P. Gardner, Jesse H. Goldberg, Moritz Helmstaedter, Shaul Hestrin, Fuyuki Karube, Zoltán F. Kisvárday, Bertrand Lambolez, David A. Lewis, Oscar Marin, Henry Markram, Alberto Muñoz, Adam Packer, Carl C. H. Petersen, Kathleen S. Rockland, Jean Rossier, Bernardo Rudy, Peter Somogyi, Jochen F. Staiger, Gabor Tamas, Alex M. Thomson, Maria Toledo-Rodriguez, Yun Wang, David C. West and Rafael Yuste, Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex, Nature Reviews Neuroscience 9: 557-568, (2008) [pdf] [abstract]

Cyril Monier, Julien Fournier and Yves Frégnac, In vitro and in vivo measures of evoked excitatory and inhibitory conductance dynamics in sensory cortices, Journal of Neuroscience Methods 169: 323-365 , (2008) [pdf] [abstract]

Romain Brette, Zuzanna Piwkowska, Cyril Monier, Michelle Rudolph, Julien Fournier, Manuel Levy, Yves Frégnac, Thierry Bal and Alain Destexhe, High-Resolution Intracellular Recordings Using a Real-Time Computational Model of the Electrode, Neuron 59: 379-391, (2008) [pdf] [abstract]

Martin Pospischil, Maria Toledo-Rodriguez, Cyril Monier, Zuzanna Piwkowska, Thierry Bal, Yves Frégnac, Henry Markram and Alain Destexhe, Minimal Hodgkin–Huxley type models for different classes of cortical and thalamic neurons, Biological Cybernetics 99: 427-441, (2008) [pdf] [abstract]

2007

Olivier Faugeras, Yves Frégnac and Manuel Samuelides, A future for systems and computational neuroscience in France?, J Physiol Paris 101: 1-8, (2007) [pdf] [abstract]

2006

Mathilde Badoual, Quan Zou, Andrew Davison, Michelle Rudolph, Thierry Bal, Yves Frégnac and Alain Destexhe, Biophysical and phenomenological models of multiple spike interactions in spike-timing dependent plasticity, Int J Neural Syst 16: 79-97, (2006) [pdf] [abstract]

Andrew Davison and Yves Frégnac, Learning cross-modal spatial transformations through spike timing-dependent plasticity, J Neurosci 26: 5604-15, (2006) [pdf] [abstract]

2004

Yves Frégnac and Thierry Bal, From neuronal assemblies to cyborgs, Journal of Physiology - Paris 98: 293-295, (2004) [pdf]

Yves Frégnac, From synaptic rumours to low-level perception: an intracellular view of visual cortical dynamics, Progress in Biochemistry and Biophysic 31: 6-8, (2004)

Yves Frégnac, Alice René, Jean Baptiste Durand and Yves Trotter, Brain encoding and representation of 3D-space using different senses, in different species, J Physiol Paris 98: 1-18, (2004) [pdf]

2003

Yves Frégnac, Cyril Monier, Frédéric Chavane, Pierre Baudot and Lyle Graham, Shunting inhibition, a silent step in visual cortical computation, J Physiol Paris 97: 441-51, (2003) [pdf] [abstract]

Cyril Monier, Frédéric Chavane, Pierre Baudot, Lyle Graham and Yves Frégnac, Orientation and direction selectivity of synaptic inputs in visual cortical neurons: a diversity of combinations produces spike tuning, Neuron 37: 663-80, (2003) [pdf] [abstract]

Peggy Seriès, Jean Lorenceau and Yves Frégnac, The "silent" surround of V1 receptive fields: theory and experiments, J Physiol Paris 97: 453-74, (2003) [pdf] [abstract]

Yves Frégnac, Neurogeometry and entoptic visions of the functional architecture of the brain, J Physiol Paris 97: 87-92, (2003) [pdf]

Nicolas Brunel, Yves Frégnac, Claude Meunier and Jean Pierre Nadal, Neuroscience and computation, J Physiol Paris 97: 387-90, (2003) [pdf]

2002

Sébastien Georges, Peggy Seriès, Yves Frégnac and Jean Lorenceau, Orientation dependent modulation of apparent speed: psychophysical evidence, Vision Res 42: 2757-72, (2002) [pdf] [abstract]

Peggy Seriès, Sébastien Georges, Jean Lorenceau and Yves Frégnac, Orientation dependent modulation of apparent speed: a model based on the dynamics of feed-forward and horizontal connectivity in V1 cortex, Vision Res 42: 2781-97, (2002) [pdf] [abstract]

Yves Frégnac, A conceptual framework of Hebbian assemblies, Nature Cognitive Science. 2: 320-329, (2002)

2001

Peggy Seriès, Sébastien Georges, Jean Lorenceau and Yves Frégnac, A network view of the structure of center/surround modulations of V1 receptive field properties in visual and cortical spaces, Neurocomputing. 38-40: 881-888, (2001)

Francis C. Colpaert and Yves Frégnac, Paradoxical signal transduction in neurobiological systems, Mol Neurobiol 24: 145-68, (2001) [pdf] [abstract]

2000

Frédéric Chavane, Cyril Monier, Vincent Bringuier, Pierre Baudot, Lyle J. Borg-Graham, Jean Lorenceau and Yves Frégnac, The visual cortical association field: a Gestalt concept or a psychophysiological entity, J Physiol Paris 94: 333-42, (2000) [pdf] [abstract]

1999

Yves Frégnac and Daniel Shulz, Activity-dependent regulation of receptive field properties of cat area 17 by supervised Hebbian learning, J Neurobiol 41: 69-82, (1999) [pdf] [abstract]

Yves Frégnac, A tale of two spikes, Nat Neurosci 2: 299-301, (1999) [pdf]

Vincent Bringuier, Frédéric Chavane, Larry Glaeser and Yves Frégnac, Horizontal propagation of visual activity in the synaptic integration field of area 17 neurons, Science 283: 695-9, (1999) [pdf] [abstract]

1998

N Gazeres, Lyle J. Borg-Graham and Yves Frégnac, A phenomenological model of visually evoked spike trains in cat geniculate nonlagged X-cells, Vis Neurosci 15: 1157-74, (1998) [abstract]

Dominique Debanne, Daniel Shulz and Yves Frégnac, Activity-dependent regulation of 'on' and 'off' responses in cat visual cortical receptive fields, J Physiol 508 ( Pt 2): 523-48, (1998) [pdf] [abstract]

Yves Frégnac, Homeostasis or synaptic plasticity, Nature 391: 845-6, (1998) [pdf]

Lyle J. Borg-Graham, Cyril Monier and Yves Frégnac, Visual input evokes transient and strong shunting inhibition in visual cortical neurons, Nature 393: 369-73, (1998) [pdf] [abstract]

1997

Vincent Bringuier, Yves Frégnac, Attila Baranyi, Dominique Debanne and Daniel Shulz, Synaptic origin and stimulus dependency of neuronal oscillatory activity in the primary visual cortex of the cat, J Physiol 500 ( Pt 3): 751-74, (1997) [pdf] [abstract]

1996

Yves Frégnac, Vincent Bringuier and Frédéric Chavane, Synaptic integration fields and associative plasticity of visual cortical cells in vivo, J Physiol Paris 90: 367-72, (1996) [pdf] [abstract]

Yves Frégnac, Vincent Bringuier, Frédéric Chavane, Larry Glaeser and Jean Lorenceau, An intracellular study of space and time representation in primary visual cortical receptive fields, J Physiol Paris 90: 189-97, (1996) [abstract]

Yves Frégnac, Dynamics of functional connectivity in visual cortical networks: an overview, J Physiol Paris 90: 113-39, (1996) [pdf] [abstract]

Lyle J. Borg-Graham, Cyril Monier and Yves Frégnac, Voltage-clamp measurement of visually-evoked conductances with whole-cell patch recordings in primary visual cortex, J Physiol Paris 90: 185-8, (1996) [pdf] [abstract]

1995

Dominique Debanne, Daniel Shulz and Yves Frégnac, Temporal constraints in associative synaptic plasticity in hippocampus and neocortex, Can J Physiol Pharmacol 73: 1295-311, (1995) [abstract]

1994

Yves Frégnac, John P. Burke, D Smith and Michael J. Friedlander, Temporal covariance of pre- and postsynaptic activity regulates functional connectivity in the visual cortex, J Neurophysiol 71: 1403-21, (1994) [abstract]

1993

Michael J. Friedlander, Yves Frégnac and John P. Burke, Temporal covariance of postsynaptic membrane potential and synaptic input--role in synaptic efficacy in visual cortex, Prog Brain Res 95: 207-23, (1993)

Daniel Shulz, Dominique Debanne and Yves Frégnac, Cortical convergence of ON- and OFF-pathways and functional adaptation of receptive field organization in cat area 17, Prog Brain Res 95: 191-205, (1993)

1992

Yves Frégnac, Daniel Shulz, Simon Thorpe and Elie Bienenstock, Cellular analogs of visual cortical epigenesis. I. Plasticity of orientation selectivity, J Neurosci 12: 1280-300, (1992) [pdf] [abstract]

Daniel Shulz and Yves Frégnac, Cellular analogs of visual cortical epigenesis. II. Plasticity of binocular integration, J Neurosci 12: 1301-18, (1992) [pdf] [abstract]

Vincent Bringuier, Yves Frégnac, Dominique Debanne, Daniel Shulz and Attila Baranyi, Synaptic origin of rhythmic visually evoked activity in kitten area 17 neurones, Neuroreport 3: 1065-8, (1992) [abstract]

1989

Damien Davenne, Yves Frégnac, Michel Imbert and Joelle Adrien, Lesion of the PGO pathways in the kitten. II. Impairment of physiological and morphological maturation of the lateral geniculate nucleus, Brain Res 485: 267-77, (1989) [abstract]

1988

Yves Frégnac, Daniel Shulz, Simon Thorpe and Elie Bienenstock, A cellular analogue of visual cortical plasticity, Nature 333: 367-70, (1988) [abstract]

Yves Frégnac and Daniel E. Shulz, Synapses of Hebb and epigenesis of the visual cortex, Arch Int Physiol Biochim 96: A175-7, (1988)

1987

Yves Trotter, Yves Frégnac and P Buisseret, The period of susceptibility of visual cortical binocularity to unilateral proprioceptive deafferentation of extraocular muscles, J Neurophysiol 58: 795-815, (1987) [abstract]

Adrienne L. Graves, Yves Trotter and Yves Frégnac, Role of extraocular muscle proprioception in the development of depth perception in cats, J Neurophysiol 58: 816-31, (1987) [abstract]

1984

Yves Frégnac and Michel Imbert, Development of neuronal selectivity in primary visual cortex of cat, Physiol Rev 64: 325-434, (1984)

Joelle Adrien, Gérard Blanc, P Buisseret, Yves Frégnac, E Gary-Bobo, Michel Imbert, Jean Pol Tassin and Yves Trotter, Noradrenaline and functional plasticity in kitten visual cortex: a re-examination, J Physiol 367: 73-98, (1984) [pdf] [abstract]

1983

Michel Imbert and Yves Frégnac, Specification of cortical neurons by visuomotor experience, Prog Brain Res 58: 427-36, (1983)

Yves Trotter, Yves Frégnac and P Buisseret, Synergy of vision and extraocular proprioception in the mechanisms of functional plasticity of the primary visual cortex in the kitten, C R Seances Acad Sci III 296: 665-8, (1983) [abstract]

1982

Joelle Adrien, P Buisseret, Yves Frégnac, E Gary-Bobo, Michel Imbert, Jean Pol Tassin and Yves Trotter, Noradrenaline and plasticity of the visual cortex of the kitten: a reexamination, C R Seances Acad Sci III 295: 745-50, (1982) [abstract]

Yves Frégnac, B Grandjean and E Gary-Bobo, Perceptual deficits in the cat deprived of visual experience: psychometric functions established by the conditioned suppression method, Annee Psychol 82: 29-43, (1982)

1981

Yves Frégnac, Yves Trotter, Elie Bienenstock, P Buisseret, E Gary-Bobo and Michel Imbert, Effect of neonatal unilateral enucleation on the development of orientation selectivity in the primary visual cortex of normally and dark-reared kittens, Exp Brain Res 42: 453-66, (1981) [abstract]

Yves Trotter, Yves Frégnac and P Buisseret, Period of sensitivity of the primary visual cortex of the cat to the unilateral suppression of extraocular proprioceptive afferents, C R Seances Acad Sci III 293: 245-8, (1981) [abstract]

1979

Yves Frégnac, Yves Trotter, Elie Bienenstock and Michel Imbert, Effect of neonatal unilateral enucleation on the development of orientation selectivity in kitten primary visual cortex, C R Seances Acad Sci D 289: 1073-5, (1979) [abstract]

Yves Frégnac, Development of orientation selectivity in the primary visual cortex of normally and dark reared kittens. I. Kinetics, Biol Cybern 34: 187-93, (1979) [abstract]

Yves Frégnac, Development of orientation selectivity in the primary visual cortex of normally and dark reared kittens. II. Models, Biol Cybern 34: 195-203, (1979) [abstract]

1978

Yves Frégnac and Michel Imbert, Early development of visual cortical cells in normal and dark-reared kittens: relationship between orientation selectivity and ocular dominance, J Physiol 278: 27-44, (1978) [pdf] [abstract]

Yves Frégnac, P Buisseret, Elie Bienenstock, E Gary-Bobo and Michel Imbert, Persistence of orientation-selective cells of the primary visual cortex in kittens enucleated unilaterally at birth and reared in darkness, C R Acad Sci Hebd Seances Acad Sci D 287: 149-51, (1978) [abstract]

Michel Imbert, P Buisseret, Yves Frégnac and E Gary-Bobo, Ontogeny of the properties of the cells of the visual cortex of the kitten, Arch Ital Biol 116: 370-4, (1978)

1977

Yves Frégnac, E Gary-Bobo and Michel Imbert, Stabilization of operant responses during a program of variable interval reinforcement as a preliminary investigation of sensory thresholds using conditioned suppression in the cat, C R Acad Sci Hebd Seances Acad Sci D 285: 547-50, (1977) [abstract]

Teaching (21)

2016

Yves Frégnac, Cours de Sciences Cognitives, in Cours Supélec-Centrale et Polytechnique, (2016) [abstract]

2015

Cyril Monier and Yves Frégnac, Séminaires Cerveau et Cognition, in Polytechnique, (2015) [abstract]

2014

Cyril Monier and Yves Frégnac, Séminaires Cerveau et Cognition, in Polytechnique, (2014) [abstract]

2013

Yves Frégnac and Cyril Monier, Séminaires Cerveau et Cognition, in Polytechnique, (2013) [abstract]

2012

Yves Frégnac and Cyril Monier, Séminaires Cerveau et Cognition, in Département d'Humanités et Sciences Sociales - Ecole Polytechnique, (2012) [abstract]

Yves Frégnac, Cours de Sciences Cognitives, in SUPELEC, (2012) [abstract]

2011

Yves Frégnac, Cours de Sciences Cognitives, in Département d'Humanités et Sciences Sociales - Ecole Polytechnique., (2011) [abstract]

Yves Frégnac and Cyril Monier, Séminaires Cerveau et Cognition, in Département d'Humanités et Sciences Sociales - Ecole Polytechnique., (2011) [abstract]

2010

Yves Frégnac and René Doursat, Séminaires Cerveau et Cognition, in Département d'Humanités et Sciences Sociales - Ecole Polytechnique., (2010) [abstract]

2009

Yves Frégnac, Cours de Sciences Cognitives, in Département d'Humanités et Sciences Sociales - Ecole Polytechnique., (2009) [abstract]

Yves Frégnac and René Doursat, Séminaires Cerveau et Cognition, in Département d'Humanités et Sciences Sociales - Ecole Polytechnique., (2009) [abstract]

2002

Yves Frégnac and Alain Destexhe, Neurosciences Intégratives et Computationnelles, in DEA Interface Physique - Biologie (Paris XI), (2002)

2001

Yves Frégnac and Alain Destexhe, Cours de Neurosciences, in DEA Neurosciences et Sciences Cognitives (Paris VI), (2001)

2000

Yves Frégnac, Les Mécanismes cérébraux de la Vision, in Formation Continue en Optométrie (D.U) Sciences de la Vision (Orsay), Ecole polytechnique, Magistère de Biologie-Biochimie,1ère année (Ecole Normale supérieure) depuis , (2000)

Yves Frégnac, Neurobiologie des fonctions cognitives, in DEA de Sciences Cognitives, (Paris XI) depuis , (2000)

Yves Frégnac and Alain Destexhe, Réseaux Neuronaux, in DEA Interface Physique-Biologie (Paris XI), (2000)

Yves Frégnac, Cerveau et Cognition, in Responsable de l'enseignement de Biologie de 2ème année (Ecole Supérieur d'Electricité) depuis , (2000)

1999

Daniel Shulz, Yves Frégnac, C Milleret, Marc Pananceau, G Soubrane and Yves Trotter, Neurophysiologie de la vision et développement du système visuel depuis, in D.U. Sciences de la vision (Formation permanente, Université Paris-Sud), (1999)

1998

Yves Frégnac and Thierry Bal, Dynamique de Réseaux Neuronaux, in DEA de Neurosciences et DEA de Sciences Cognitives (Paris VI) , (1998)

Yves Frégnac and Thierry Bal, Neurosciences Intégratives et Computationnelles, in DEA Interface Physique - Biologie (Paris XI), (1998)

1994

Daniel Shulz and Yves Frégnac, De la sensation à la perception, in Magistère Biologie et Biochimie (Ecole Normale Supérieure Paris) depuis, (1994)

Presentations (136)

2012

Yves Frégnac and Cyril Monier, Séminaires Cerveau et Cognition, Talk At: Cerveau et Cognition 2012, (Ecole Polytechnique) (2012) [abstract]

2011

Esin Yavuz, Cyril Monier and Yves Frégnac, Mesoscopic Correlations between Ongoing and Evoked States, Revealed by Voltage Sensitive Dye Imaging in Primary Visual Cortex, Talk At: Brain-i-nets project meeting, (Gif sur Yvette (France)) (2011)

Esin Yavuz, Cyril Monier and Yves Frégnac, Dependency of Evoked Dynamics on Sensory Input Statistics, Revealed by Voltage Sensitive Dye Imaging in Primary Visual Cortex, Poster At: ED3C meeting, (Roscoff (France)) (2011)

Florian Gerard-Mercier, Pedro Carelli, Marc Pananceau, Aurélie Daret and Yves Frégnac, New insights on the dynamic cortical association field in the cat primary visual cortex., Poster At: 8th IBRO World Congress of Neuroscience, (Florence (Italy)) (2011)

Marc Pananceau, Pedro Carelli, Florian Gerard-Mercier, Aurélie Daret and Yves Frégnac, New vistas on the dynamic cortical association field in the cat primary visual cortex, Poster At: Colloque de la Société Française des Neurosciences, (Marseille (France)) (2011)

Gerald Hahn, Cyril Monier and Yves Frégnac, Criticality and avalanches in V1 network dynamics using multi-electrode array and local field potential measurements, Talk At: Brain-i-Nets meetings March 2011, (Gif sur Yvette (France)) (2011)

2010

Esin Yavuz, Cyril Monier and Yves Frégnac, Multiscale Analysis of Visual Cortical Dynamics Using Network Imaging and Multiple Simultaneous Recordings , Talk At: Ecole Neuroscience de Paris, (Paris (France)) (2010)

Esin Yavuz, Cyril Monier and Yves Frégnac, Multiscale Analysis of Visual Cortical Dynamics Using Network Imaging, Talk At: FACETS 4th Plenary Meeting , (Dresde (Germany)) (2010)

Andrew Davison, Thierry Brizzi, Olivier Manette, Cyril Monier and Yves Frégnac, Helmholtz: a modular tool for neuroscience databases, Poster At: Front. Neurosci. Conference Abstract Neuroinformatics, (Kobe (Japan)) (2010)

Pedro Carelli, Marc Pananceau, Florian Mercier, Cyril Monier and Yves Frégnac, Mapping collinear subthreshold facilitation using sparse apparent motion noise, Poster At: American Society for Neuroscience, (San Diego (USA)) (2010)

Sébastien Béhuret, Leonel Gomez, Yves Frégnac and Thierry Bal, Context-dependent information transfer in model thalamocortical circuits, Poster At: FACETS, (Paris (France)) (2010)

Sébastien Béhuret, Leonel Gomez, Yves Frégnac and Thierry Bal, Context-dependent information transfer in model thalamocortical circuits, Poster At: NEUROBIOLOGY CONFERENCES LADISLAV TAUC , (Gif sur Yvette (France)) (2010)

Sébastien Béhuret, Leonel Gomez, Yves Frégnac and Thierry Bal, Context-dependency in the transfer of sensoryt information transfer in thalamo-cortico-thalamical circuits, Poster At: 7th Forum of European Neuroscience, (Amsterdam (Holland)) (2010)

Pierre-Jean Arduin, Valerie Ego-Stengel, Daniel Shulz and Yves Frégnac, Graded control of a prosthesis by operant conditioning of single-units in rat motor cortex, Poster At: Ecole des Neurosciences de Paris, (Paris (France)) (2010)

Yves Frégnac, Multi-scale analysis of stimulus-dependency of V1 cortical dynamics, Invited Talk At: 1st International workshop on the shapes of Brain dynamics, (Paris (France)) (2010)

Yves Frégnac, A polymorphic view of visual cortical dynamics: from "crystal" to "smoke", Invited Talk At: The Denise Fessard Lecture. Société Brésilienne de Neuroscience, (Caxambu (Brazil)) (2010)

Yves Frégnac, Revisiting Visual Cortex: from Simple to Complex, Invited Talk At: Simpósio França-Brasil: Société des Neurosciences (França) e Sociedade Brasileira de Neurociências e Comportamento , (Caxambu (Brazil)) (2010)

Yves Frégnac, Simpleness in V1 receptive fields, a mirror of visual input complexity ? , Invited Talk At: nstitute for Adaptive and Neural Computation. School of Informatics, (Edinburgh (UK)) (2010)

Yves Frégnac, A polymorphic view of visual cortical dynamics: from "crystal" to "smoke", Invited Talk At: Frontiers in Neuromorphic Computation: a Multi-FACETS Enterprise , (Paris (France)) (2010)

Yves Frégnac, Functional polymorphy of visual cortical dynamics: from "crystal" to "smoke". , Invited Talk At: Symposium in the honour of Olivier Faugeras, (Sophia Antipolis - Méditerranée (France)) (2010)

Yves Frégnac, Series of talks and Chairs. Problem of the day (co-chair with Giacomo Indiveri and Rodney Douglas): Neural computation, architectures, and function. Problem of the day (co-chair with Thomas Wenneker and Jean-Jacques Slotine) : Event-based processing in neural systems., Invited Talk At: CapoCaccia Cognitive Neuromorphic Engineering Workshop, (Sardinia (Italy)) (2010)

Yves Frégnac, Neurogéométrie de la Vision, Invited Talk At: Séminaire d’épistémologie des sciences cognitives, (Lyon (France)) (2010)

Yves Frégnac, Neuromorphic computation for Vision, Invited Talk At: Seven Keys to the Digital Future, (Edinburgh (UK)) (2010)

Yves Frégnac, Diversity in neuromorphic computation and compositionality in cortical dynamics., Invited Talk At: Chaire d’Informatique et sciences numériques , (Paris (France)) (2010)

Florian Gerard-Mercier, Pedro Carelli, Aurélie Daret, Marc Pananceau, Cyril Monier and Yves Frégnac, Apparent motion noise as a functional probe of the dynamic association field in visual cortical neurons, Poster At: Conférence TAUC "De l'Analyse Mathématique des Images à la Neurogéométrie du Cerveau.", (Gif sur Yvette (France)) (2010)

Cyril Monier, Julien Fournier, Esin Yavuz, Gerald Hahn and Yves Frégnac, Multiscale analysis of stimulus dependency of visual response reliability in V1 cortex. , Poster At: Society for Neuroscience Meeting, (San Diego (USA)) (2010)

2009

Pierre Yger, Sami El Boustani, Olivier Marre, Andrew Davison, Alain Destexhe and Yves Frégnac, Spatial organization of evoked neuronal dynamics in 2D recurrent networks, with or without structured stimulation, Poster At: BMC Neuroscience 10 , (Berlin (Germany)) (2009)

Pierre Yger, Sami El Boustani, Yves Frégnac and Alain Destexhe, A mean-field based formalism for modeling and analysis of voltage-sensitive dye imaging data, Poster At: American Society for Neuroscience , (Chicago (USA)) (2009)

Pierre Yger, Sami El Boustani, Olivier Marre, Andrew Davison, Alain Destexhe and Yves Frégnac, Spatial organization of evoked neuronal dynamics in 2D recurrent networks, with or without structured stimulation, Poster At: Eighteenth Annual Computational Neuroscience Meeting, (Berlin (Germany)) (2009)

Esin Yavuz, Cyril Monier and Yves Frégnac, Blind Signal Separation Methods for VSD, Talk At: FACETS Workshop « Macroscopic Aspects of Neuronal Activity: VSD, LFP and Macroscopic Models », (Marseille (France)) (2009)

Manuel Levy, Anthony Truchard, Gérard Sadoc, I Ohzawa, Yves Frégnac and Ralph Freeman, Dynamics of nonlinear suppression in Cat V1 Simple cells, Poster At: American Society for Neuroscience Abstract, (Chicago (USA)) (2009)

Manuel Levy, Anthony Truchard, Gérard Sadoc, I Ohzawa, Yves Frégnac and Ralph Freeman, Dynamics of nonlinear suppression in Cat V1 Simple cells, Poster At: Annual Meeting Computational Neuroscience Society, (Berlin (Germany)) (2009)

Jens Kremkow, Laurent Perrinet, Cyril Monier, Yves Frégnac, Gwendal Le Masson and A Aertsen, Control of the temporal interplay between excitation and inhibition by the statisitics of visual input, Poster At: Annual Meeting Computational Neuroscience Society , (Berlin (Germany)) (2009)

Julien Fournier, Cyril Monier, Manuel Levy, Marc Pananceau and Yves Frégnac, Control of the “Effective” receptive field organization by the spatio-temporal statistics of the visual input, Poster At: American Society for Neuroscience Abstract, (Chicago (USA)) (2009)

Sami El Boustani, Pierre Yger, Yves Frégnac and Alain Destexhe, A mean-field based formalism to investigate structure-function correlations in sensory neocortex using VSD imaging, Poster At: American Society for Neuroscience Abstract, (Chicago (USA)) (2009)

Pedro Carelli, Marc Pananceau, Irina Kopysova and Yves Frégnac, Mapping the horizontal synaptic association field with apparent motion in the cat visual cortex, Poster At: American Society for Neuroscience Abstract, (Chicago (USA)) (2009)

Thierry Bal, Sébastien Béhuret, Charlotte Deleuze, Leonel Gomez, Zuzanna Piwkowska, Jakob Wolfart, Damien Debay, Romain Brette, Sami El Boustani, Olivier Marre, Pierre Baudot, Pierre Yger, Michelle Rudolph, Gwendal Le Masson, Gérard Sadoc, Alain Destexhe and Yves Frégnac, Hybrid biological-artificial neuronal networks, Poster At: Colloque Interface physique, chimie, biologie, soutient à la prise de risque, (Fréjus (France)) (2009)

Pierre-Jean Arduin, Daniel Shulz and Yves Frégnac, Vers une simplification du décodage de l’intention du mouvement, Poster At: Interface Cerveau –Machine , (Paris (France)) (2009)

Pierre-Jean Arduin, Valerie Ego-Stengel, Daniel Shulz and Yves Frégnac, Graded control of a prosthesis by operant conditioning of single-units in rat motor cortex, Poster At: Congrès FRM/IRME/ICM Interfaces Cerveau-Machine, (Paris (France)) (2009)

Yves Frégnac, Multiscale functional imaging of the dynamic "association field" in V1. , Invited Talk At: Journée conjointe du GDR Vision et MSPC, (Paris (France)) (2009)

Yves Frégnac, An intracellular view of the complexity of cortical computation in V1. , Invited Talk At: Barcelona Cognition, Brain, and Technology Summer School , (Barcelona (Spain)) (2009)

Yves Frégnac, Foundations of the Dynamic Association Field, Invited Talk At: Neuromathematics and Visual Cognition, (Bologna (Italy)) (2009)

Yves Frégnac, Multi-scale analysis and complexity in visual cortex, Invited Talk At: Organisation and Plasticity of the visual cortex, (Pisa (Italy)) (2009)

Yves Frégnac, Diversity, recurrency and complexity: is V1 on the verge of chaos? , Invited Talk At: BCNN, (Berlin (Germany)) (2009)

Yves Frégnac, Integrative and Computational Neurosciences: interdisciplinarity of Sciences confronted to Brain Complexity, Invited Talk At: Challenges for the XXIst century, (Paris (France)) (2009)

Yves Frégnac, Reading out the neural code by listening to the synaptic echoes of the visual world in a single cell. Rare Diseases II: Hearing and Sight Loss. , Invited Talk At: ESF-UB Conference in Biomedicine, (Sant Feliu de Guixols (Spain)) (2009)

Yves Frégnac, Concepts in dynamics of cortical sensory networks : signal, noise or chaos ?, Invited Talk At: Brain Machine Interface , (Paris (France)) (2009)

Yves Frégnac, Interfaces Cerveau – Machine, Invited Talk At: Atelier PIRSTEC, (Lyon (France)) (2009)

Yves Frégnac, Stimulus-driven Coordination of Cortical Cell Assemblies and Propagation of Gestalt Belief in V1., Invited Talk At: Ernst Strüngmann Forum , (Frankfurt/M (Germany)) (2009)

Yves Frégnac, “Noise” and information propagation in sensory cognitive networks., Invited Talk At: 5th Cajal Winter School., (Benasque (Spain) ) (2009)

Yves Frégnac, Bruit, Information et Dynamique Corticale, Invited Talk At: Séminaire de la Fondation Bull Cerveau-Machine, (Paris (France)) (2009)

Yves Frégnac, Bruit, Information an Cortical Dynamics, Invited Talk At: "Signal and Neurons” Conférence-Débat. , (Paris (France)) (2009)

Yves Frégnac, Multi-scale analysis and complexity in sensory cortical networks. , Invited Talk At: CNRS - Max Planck Gesellshaft Symposium, (Germany) (2009)

Yves Frégnac, Propagation, Reverberation and Complexity: visual cortex near the edge of chaos? , Invited Talk At: Seminars in Neuroscience , (Alicante (Spain)) (2009)

Yves Frégnac, Complexity based computing : From Biology to Brain Models, Invited Talk At: Facets II – Thinktank Meeting, (Leysin) (2009)

Yves Frégnac, Synthesis Report on the Biological V1, Invited Talk At: 4th Annual Meeting of the Facets Project, (Leysin) (2009)

Yves Frégnac, The Biological V1, Invited Talk At: 3rd Annual Review of the Facets Project. European Community Review Panel, (Heidelberg) (2009)

Yves Frégnac, Reconstructing perceptual waves, Invited Talk At: les défis du XXIème siècle: Imagerie de l’encéphale, de la cellule à l’organe, (Paris (France)) (2009)

Gerald Hahn, Thomas Petermann, Martha Havenith, Shan Yu, Dietmar Plenz, Wolf Singer, Yves Frégnac and Danko Nikolic, Neuronal avalanches in vivo, Talk At: Yuste Lab June 2009, (Columbia University (USA)) (2009)

2008

Pierre Yger, Abigail Morrison, Markus Diesmann, Andrew Davison and Yves Frégnac, STDP in topogra-phical neuronal networks, Poster At: RIKEN BSI Workshop, (Wako (Japan)) (2008)

David Colliaux, Cyril Monier, Nazied Huguet, Marc Pananceau, J Petitot and Yves Frégnac, A phenomenological model of ongoing dynamics in V1 cortex, Poster At: Conférence Ladislav TAUC. Complexity in neural network dynamics, (Gif sur Yvette (France)) (2008)

David Colliaux, Cyril Monier, Yves Frégnac and J Petitot, Phenomenology of neocortical neurons dynamics, Poster At: Riken BSI Workshop, (Wako, Japan) (2008)

Pierre-Jean Arduin, Valerie Ego-Stengel, Daniel Shulz and Yves Frégnac, Graded control of a prosthesis by operant conditioning of single-units in rat motor cortex, Poster At: Ecole Doctorale des Frontières du Vivant, (Dourdan (France)) (2008)

Yves Frégnac, Multiscale approaches of functional complexity in visual cortex, Invited Talk At: NeuroSpin Conferences , (Saclay (France)) (2008)

Yves Frégnac, Défense du renouvellement du contrat Européen FACETS, Invited Talk At: Communauté Européenne, (Bruxelles, Belgique) (2008)

Thierry Bal, Zuzanna Piwkowska, Romain Brette, Jakob Wolfart, Damien Debay, Cyril Monier, Michelle Rudolph, Julien Fournier, Manuel Levy, Yves Frégnac, Alain Destexhe and Gwendal Le Masson, Thalamocortical hybrid networks and an introduction to Active Electrode Compensation., Invited Talk At: Meeting of the Physiological Society, Techniques Workshop, (University of Cambridge) (2008)

Pierre Yger, Andrew Davison and Yves Frégnac, PyNN: a common Python interface for network simulators. , Poster At: 17th Annual Computational Neuroscience Meeting , (Portland (USA)) (2008)

Jens Kremkow , Laurent Perrinet, Pierre Baudot, Manuel Levy, Olivier Marre, Cyril Monier, Yves Frégnac, G Masson and A Aertsen, Control of the temporal interplay between excitation and inhibition by the statistics of visual input: a V1 network modelling study. , Poster At: Society for Neuroscience Abstracts 34, (Washington DC (USA)) (2008)

Romain Brette, Zuzanna Piwkowska, J.F Gomez-Gonzalez, Cyril Monier, Michelle Rudolph, Julien Fournier, Manuel Levy, Yves Frégnac, Thierry Bal and Alain Destexhe, Active Electrode Compensation for high-resolution intracellular recordings in vitro and in vivo, Poster At: Society for Neuroscience Abstracts 34, (Washington DC (USA)) (2008)

Yves Frégnac, Multiscale approaches in systems and computational neuroscience, Invited Talk At: DIM Bionanophotonique « Micro et nanotechnologies pour les Neurosciences » , (Paris (France)) (2008)

Yves Frégnac, Interdisciplinary approaches in neural based computing, Invited Talk At: EPSRC-COLAMN Annual meeting, (Plymouth (UK)) (2008)

Yves Frégnac, Biophysical principles that support information processing in neocortical networks, Invited Talk At: Cognitive Neuromorphic Engineering Workshop, (Sardinia (Italie)) (2008)

Yves Frégnac, Multiscaling approaches in functional electrophysiology: from conductance to network dynamics, Invited Talk At: “Complexity-based computing: from biology to hardware”. International Thinktank Facets Meeting , ( Gif sur Yvette (France)) (2008)

Yves Frégnac, Diversité, récurrence et Complexité: V1 au bord du chaos? , Invited Talk At: Annual Meeting of GDR Vision, (Paris (France)) (2008)

Yves Frégnac, Synaptic echoes of visual perception, Invited Talk At: Programa Avançado em Neurociencias (PAN), (Rio de Janeiro (Brazil)) (2008)

Yves Frégnac, Extraction of computational principles from the biological study of sensory cortical dynamics. , Invited Talk At: NeuroComp 2008, (Marseille (France)) (2008)

Pierre Yger, Olivier Marre, Andrew Davison and Yves Frégnac, Reliable recall of spontaneous activity patterns in chaotic cortical networks, Poster At: NeuroComp, (Marseille) (2008) [pdf] [abstract]

2007

Yves Frégnac, Biological principles for neurocomputing architectures. , Invited Talk At: Information and Technology EC Review Meeting, (Brussels (Belgium)) (2007)

Yves Frégnac, Efficient coding and spike timing precision in V1 neurons during visual processing of natural scenes. , Invited Talk At: An interdisciplinary approach for processing texture and natural images, (Paris (France)) (2007)

Yves Frégnac, The “dynamic association field” in visual cortical neurons : a possible fit between perception and action. , Invited Talk At: 2nd Brazilian Neuroscience Meeting and International Conference, (the International Natal Neuroscience Institute (Brazil)) (2007)

Yves Frégnac, Diversity and Complexity in Neural Networks, Invited Talk At: European Advanced courses in Complexity and Neural Networks, (Génopôle d’Evry (France)) (2007)

Yves Frégnac, La machine neuronale: sélectivité et architecture fonctionnelle. , Invited Talk At: Cours de la Chaire Européenne du Collège de France , (Paris (France)) (2007)

Yves Frégnac, Reading out network dynamics in V1 by listening to synaptic echoes in a single neuron. , Invited Talk At: Joint Meeting between Facets and Daisy. Institute of Neuroinformatics, (Zürich (Allemagne)) (2007)

Yves Frégnac, Complexity in neural network dynamics: general issues, Invited Talk At: Conférence Ladislav TAUC: Complexity in neural network dynamics, ( Gif sur Yvette (France)) (2007)

Yves Frégnac, Reading out the code by listening to the synaptic echoes of the visual world in a single cell. , Invited Talk At: IRME International Symposium "From Neural Code to Brain/Machine Interface", (Gouvieux les Chantilly (France)) (2007)

Yves Frégnac, The "dynamic association field" of visual cortex neurons: a fit between natural perception and eye-movements., Invited Talk At: American Neuroscience Association Symposium: “Mechanisms and Functions of Visual Signals from Beyond the Classical Receptive Field in Primary Visual Cortex, (San Diego (USA)) (2007)

Yves Frégnac, Contextual dynamics in sensory processing: From travelling waves to constrained high conductance states for natural images., Invited Talk At: European School of Computational Neuroscience , (Arcachon (France)) (2007)

Yves Frégnac, Functional complexity and structural diversity in V1, Invited Talk At: Theoretical Neuroscience and Complex Systems, (Frankfurt (Germany)) (2007)

Yves Frégnac, The "dynamic association field" of visual cortex neurons: A possible fit between natural scene perception and eye-movement. , Invited Talk At: the Advanced Program in Neuroscience. ICB-UFRJ, (Rio-Janeiro (Bresil)) (2007)

Yves Frégnac, Functional dynamics in cortical networks, Invited Talk At: In Lecture Series at the Karolinska on “The cerebral cortex: Organization and Dynamics” , (Stockohlm (Sweden)) (2007)

Pierre Yger, Olivier Marre, Sami El Boustani, Pierre Baudot, Cyril Monier, Manuel Levy, Andrew Davison and Yves Frégnac, Chaos control: Reliable signal propagation and pattern completion in chaotic neuronal networks, Poster At: SFN, (San Diego) (2007) [pdf] [abstract]

Yves Frégnac, Inhibition and dynamic non-linearities in sensory processing. , Invited Talk At: FACETS Interneuron meeting, ( Gif sur Yvette (France)) (2007)

2006

Yves Frégnac, The receptive field concept: Attempts and failures to map function onto structure, Invited Talk At: Foundation on Evolution and Cognition , (Les Treilles (France)) (2006)

Yves Frégnac, Entoptic vision of the functional architecture of primary visual cortex, Invited Talk At: Neuromathematics and Visual Perception, (Scuola Normale Superiore of Pisa (Italy)) (2006)

Yves Frégnac, Reconstructing network dynamics and function from synaptic rumours., Invited Talk At: The functional architecture from the brain: from dendrites to networks, (Marseille (France)) (2006)

Yves Frégnac, Computational diversity and functional complexity in visual cortex: when inhibition meets excitation , Invited Talk At: European School of Computational Neuroscience, (Arcachon (France)) (2006)

Yves Frégnac, Contextual dynamics in sensory processing: From liquid computation for sparse stimuli to constrained high conductance states for natural images. , Invited Talk At: European School of Computational Neuroscience , (Arcachon (France)) (2006)

Yves Frégnac, Functional complexity and structural diversity in V1. , Invited Talk At: Theoretical Neuroscience and Complex Systems, (Frankfurt (Germany)) (2006)

Yves Frégnac, The one and thousand lives of the Hebb’s synapse. , Invited Talk At: Theoretical Neuroscience and Complex Systems, (Frankfurt (Germany)) (2006)

Yves Frégnac, Revisiting Visual cortical architecture and function : from “crystal” to “smoke”. , Invited Talk At: International Symposium of Neuroscience: Vision by Brains and Machines, (Montevideo (Uruguay)) (2006)

Yves Frégnac, Imageries en miroir de la dynamique des réseaux corticaux: de la réception à la propagation. , Invited Talk At: Journée Scientifique Annuelle de l’IFR 49, (Orsay (France)) (2006)

Yves Frégnac, What must be recorded in order to understand Cortex, Invited Talk At: The Cajal Centenary conference on the Cerebral Cortex, (Barcelona (Spain)) (2006)

Yves Frégnac, Possible role of spike-timing dependent plasticity in the genesis and adaptation of sensory cortical representations., Invited Talk At: Experimental and theoretical views on synaptic plasticity, (Lausanne (Switzerland)) (2006)

Yves Frégnac, An intracellular view of complexity in visual cortical processing: in-between “crystal” and “smoke”. , Invited Talk At: Databasing the Brain.” International Neuroinformatics Coordination Initiative , (Oslo (Sweden)) (2006)

Yves Frégnac, Computational architectures and self-organization algorithms derived from biology: what can be learnt from V1 mammalian cortex. , Invited Talk At: The Golgi centenary conference on Biologically inspired systems, (Rome (Italy)) (2006)

Yves Frégnac, Le Cerveau Neuronal. , Invited Talk At: Conférence d’intérêt général sur invitation de la Mission Nationale d’Appui en Santé Mentale, (Niort (France)) (2006)

Andrew Davison, Pierre Yger, Jason Chan, Fiona Newell and Yves Frégnac, A combined psychophysical-modelling study of the mechanisms of tactile picture perception, Poster At: CNS*2006, (Edinburgh, UK) (2006) [abstract]

2005

Andrew Davison, Ammar Belatreche, Johannes Fieres, Jason Chan, Fiona Newell and Yves Frégnac, The Two-Ring paradigm: a computational approach to multisensory code binding. , Poster At: International SenseMaker Workshop on Life-Like Perception Systems, (Derry (U.K)) (2005)

Andrew Davison and Yves Frégnac, The Two-ring paradigm: a computational approach of multisensory code binding. , Invited Talk At: International SenseMaker Workshop, (School of computing Intelligence, University of Ulster, Derry (Northern Ireland)) (2005)

Yves Frégnac, Precision of spike timing in the genesis and plasticity of sensory cortical representations, Invited Talk At: Gatsby Unit , (London (UK)) (2005)

Yves Frégnac, An intracellular view of time coding in V1 neurons during processing of natural scenes., Invited Talk At: The Neural substrates of Cognition , (Instituto Juan March Fundation) (2005)

Yves Frégnac, An intracellular view of time coding and sparseness in V1 during virtual oculomotor exploration of natural scenes, Invited Talk At: 2nd International Cosyne Conference in Computational and Systems Neuroscience, (Salt Lake City, Utah (USA)) (2005)

Yves Frégnac, Olivier Marre, Pierre Baudot and Manuel Levy, Sparse representation and time coding in V1, when processing continuous streams of animated sequences of natural images. , Invited Talk At: International SenseMaker Workshop , (School of computing Intelligence, University of Ulster, Derry (Northern Ireland)) (2005)

Yves Frégnac, Physical Foundations of neurogeometry : the synaptic signature of the « association field » of visual cortical neurons. , Invited Talk At: Ecole d’été « Mathématiques et Cerveau » , (Institut Henri Poincaré, Paris (France)) (2005)

Yves Frégnac, Computational diversity and functional complexity in visual cortex: when inhibition meets excitation , Invited Talk At: European School of Computational Neuroscience , (Arcachon (France)) (2005)

Yves Frégnac, Contextual dynamics in sensory processing: From liquid computation for sparse stimuli to constrained high conductance states for natural images. , Invited Talk At: European School of Computational Neuroscience , (Arcachon (France)) (2005)

Yves Frégnac, An intracellular view of complexity in Visual Cortical processing: in-between « crystal and smoke »., Invited Talk At: Bernstein Center for Computational Neuroscience, (Freiburg (Germany)) (2005)

Yves Frégnac, Dominance of synaptically driven states on the electrical signature of cortical neurons in vivo. , Invited Talk At: Nomenclature of neocortical interneurons, (Petilla de Aragón, Navarra (Spain)) (2005)

Yves Frégnac, Revisiting issues on computational diversity and functional complexity. , Invited Talk At: Conférence annuelle DYVA, (Marseille (France)) (2005)

Yves Frégnac, The “Two-Ring” Problem: Biology, Invited Talk At: Final Defense Report of Sense-Maker, (Brussels (Belgium)) (2005)

Yves Frégnac, Architecture fonctionnelle du Cortex Visuel, Invited Talk At: Séminaire d’intérêt général à l'Ecole Polytechnique, (Palaiseau (France)) (2005)

Olivier Marre, Pierre Baudot, Manuel Levy and Yves Frégnac, High timing precision and reliability, low redundancy, and low entropy code in V1 neurons during visual processing of natural scenes., Poster At: SFN, (Washington, DC) (2005)

Andrew Davison, Ammar Belatreche, Johannes Fieres, Jason Chan, Fiona Newell and Yves Frégnac, The Two-Ring paradigm: a computational approach to multisensory code binding, Talk At: International SenseMaker Workshop on Life-Like Perception Systems, (Derry, UK) (2005) [abstract]

2004

Yves Frégnac, Architectures computationnelles dans le cortex visuel primaire et rumeurs synaptiques de la perception., Invited Talk At: IFR “Sciences du Cerveau et de la Cognition, (Marseille (France)) (2004)

Yves Frégnac, Compléxité et Hiérarchie de niveaux dans les ensembles neuronaux, Invited Talk At: Colloque de Prospective: Vers une Science des Systèmes Complexes. Symposium de prospective sur la Complexité, (Paris (France)) (2004)

Yves Frégnac, Computational architectures in primary visual cortex: from synaptic rumours to low-level perception, Invited Talk At: Research Seminar Series, (Centre for Theoretical and Computational Neuroscience, Plymouth (UK)) (2004)

Yves Frégnac, Architectures perceptives dans le cortex visuel primaire : genèse et dynamique de la rumeur synaptique., Invited Talk At: Visualiser et modéliser le cerveau, (Département d’Informatique ENS – Odyssée (INRIA), Paris (France)) (2004)

Yves Frégnac, Binding the waves, an elementary step in visual cortical perception., Invited Talk At: Oscillations and waves in cells and cell networks, (Cargèse, Corsica (France)) (2004)

Yves Frégnac, Computational architectures in visual cortex: from synaptic rumours to the genesis of orientation selectivity. , Invited Talk At: Representation of Reality by Brain an Machines: Crossed views from Neurosciences and Computer Vision, (Montevideo (Uruguay)) (2004)

Yves Frégnac, Binding and shaping cortical waves: from synaptic rumours to the genesis of perceptual association fields, Invited Talk At: Representation of Reality by Brain an Machines: Crossed views from Neurosciences and Computer Vision, (Montevideo (Uruguay)) (2004)

Yves Frégnac, Reading cortical codes and network dynamics from inside a single cell: What V1 cortical cells tell us on stars, stripes and natural images. , Invited Talk At: Psychophysical and physiological studies of the cortical association field“. International Vision Symposium, (Institute of Neuroscience, Science Academy of China, Shangai (China)) (2004)

Pierre Baudot, Manuel Levy, Olivier Marre and Yves Frégnac, An intracellular study of the temporal encoding of natural stimuli in V1 neurons., Poster At: Gordon Research Conference, (Oxford, England) (2004)

Manuel Levy, Pierre Baudot, Marc Pananceau, Olivier Marre, Nazied Huguet, Alice René and Yves Frégnac, An intracellular study of the temporal encoding of contrast in cat visual cortex during viewing of natural scenes. , Poster At: SFN, (San Diego, California) (2004)

Yves Frégnac, From synaptic rumours to low-level perception: an intracellular view of visual cortical dynamics, Invited Talk At: Third Asian Conference on Vision, (ChongQing (China)) (2004)

Andrew Davison and Yves Frégnac, Training a network of spiking neurons to perform coordinate transformations, Poster At: SfN, ( San Diego, California) (2004)

2002

Alice René, Manuel Levy, Marc Pananceau, Pierre Baudot, Nazied Huguet, V Tsoyama and Yves Frégnac, Reconfiguration of cortical synaptic dynamics following theta-burst activation of the LGN, Poster At: SFN, (Orlando, Florida) (2002)

Book Chapters (18)

2016

Yves Frégnac, Julien Fournier, Florian Gerard-Mercier, Cyril Monier, Marc Pananceau, Pedro Carelli and Xoana Troncoso, The Visual Brain: Computing Through Multiscale Complexity, In: Micro-, Meso- and Macro-Dynamics of the Brain (G. Buzsáki and Y. Christen) Springer 43-57, (2016) [pdf]

2010

Daniel Shulz and Yves Frégnac, From sensation to perception, In: Encyclopedia of Behavioural Neuroscience (GF Koob, M Le Moal and RF Thompson ) Elsevier Vol 1: 550-558, (2010)

Yves Frégnac, Pierre Baudot, Frédéric Chavane, Jean Lorenceau, Olivier Marre, Cyril Monier, Marc Pananceau, Pedro Carelli and Gérard Sadoc, Multiscale functional imaging in V1 and cortical correlates of apparent motion., In: Dynamics of visual motion processing (G. Masson and U. Ilg) Springer 73-94, (2010)

Edvard I. Moser, Maurizio Corbetta, Robert Desimone, Yves Frégnac, Pascal Fries, Ann M. Grabiel, John-Dylan Haynes, Laurent Itti, Lucia Melloni, Hannah Monyer, Wolf Singer, Christoph Von Der Malsburg and Matthew Wilson, Coordination in brain systems, In: Dynamic Coordination in the Brain: From Neurons to Mind (Christoph von der Malsburg,William A. Phillips,Wolf Singer) MIT Press 193-214, (2010)

Yves Frégnac, Pedro Carelli, Marc Pananceau and Cyril Monier, Stimulus-driven coordination of cortical cell assemblies and propagation of gestalt belief in V1, In: Dynamic Coordination in the Brain: From Neurons to Mind (Christoph von der Malsburg,William A. Phillips,Wolf Singer) MIT Press 169-192, (2010)

2009

Romain Brette, Zuzanna Piwkowska, Cyril Monier, Jose Gomez, Yves Frégnac, Thierry Bal and Alain Destexhe, Dynamic clamp with high resistance electrodes using active electrode compensation in vitro and in vivo. , In: Dynamic-clamp: From Principles to Applications (Destexhe Alain and Bal Thierry) Springer, new York 347-382, (2009)

2006

Yves Frégnac, Michelle Rudolph, Andrew Davison and Alain Destexhe, Complexity in Neuronal Networks, In: Biological Networks (François Képès) World Scientific 291-338, (2006) [pdf]

2005

Yves Frégnac, M Blatow, Jean Pierre Changeux, J Felipe, Anders Lansner, W Maass, Henry Markram, D Cormick, C Michel, Hannah Monyer and Rafael Yuste, Ups and downs in the genesis of cortical computation, In: Microcircuits: The Interface between Neurons and Global Brain Function Microcircuits: Dahlem Workshop Report 93. (Eds. Grillner, S. et al.) MIT Press 397-437, (2005)

2003

Yves Frégnac, Cyril Monier, Frédéric Chavane, Pierre Baudot and Lyle Graham, Diversity of computation of orientation and direction preference by visual cortical neurons: an intracellular re-examination, In: The Neural Basis of early Vision. (Eds. A. Kaneko) Springer-Verlag 68-69, (2003)

2002

Yves Frégnac, Hebbian synaptic plasticity, In: Handbook of Brain Theory and Neural Networks, 2nd edition. (Eds. M. A. Arbib) MIT Press 515-522, (2002)

Yves Frégnac, Cyril Monier, Frédéric Chavane, Pierre Baudot and Lyle Graham, Diversity of computation of orientation and direction preference by visual cortical neurons: an intracellular re-examination, In: The Neural Basis of early Vision. (Eds. A. Kaneko) Springer-Verlag 68-69, (2002)

Yves Frégnac, Hebbian cell assemblies, In: Nature Cognitive Science Encyclopedia () 320-329, (2002)

2001

Lyle Graham, Cyril Monier and Yves Frégnac, Now you see it, Now you don't: Shunting inhibition in early vision, In: Vision: The Approach of Biophysics and Neuroscience, Volume 11. (Eds. C. Musio) World Scientific Publishing 283-299, (2001)

1998

K Fox, Elie Bienenstock, T Bonhoeffer, J Byrne, M Davis, Yves Frégnac, A Gierer, M Mauk, C Shatz and M Stryker, To what extent are activity-dependent processes common to development and learning , In: Mechanistic Relationships between Development and Learning. (Eds. T. Carew, R. Menzel and C. J. Shatz) J. Wiley and Sons 163-188, (1998)

Yves Frégnac and Elie Bienenstock, Correlational models of synaptic plasticity: develoment, learning and cortical dynamics of mental representation, In: Mechanistic Relationships between Development and Learning: Beyond Metaphor, Dahlem Konferenzen. (Eds. T. Carew R. Menzel and C. J. Shatz ) Chichester: J. Wiley and Sons 113-148, (1998)

1996

Yves Frégnac and Vincent Bringuier, Spatio-temporal dynamics of synaptic integration in cat visual cortical receptive fields, In: Brain Theory: Biological basis and computational theory of Vision (A. Aertsen and V. Braitenberg) Springer-Verlag 143-199, (1996)

1994

Yves Frégnac and Daniel Shulz, Models of Synaptic Plasticity and Cellular Analogs of Learning in the Developing and Adult Vertebrate Visual Cortex, In: Advances in Neural and Behavioral Development (V. Casagrande and P.G. Shinkman) Ablex Publ. 149-235, (1994) [pdf]

1987

Yves Frégnac, Cellular mechanisms of epigenesis in kitten visual cortex, In: Imprinting and cortical plasticity (J.P. Rauschecker and P. Marler) John Wiley and Sons 221-266, (1987)